Two cases of multiple ossifying fibromas in the jaws. Central cementoossifying fibroma of posterior maxilla yaga us. There were several reports on cementifying fibroma combined with odontoma in the same mandible 9, 10, but cementifying fibroma coexisted with cementoblastoma were not found. Cementoossifying fibroma is a benign fibroosseous maxillary tumor belonging to the same category as fibrous dysplasia and. Report of two cases shipra arora, arundeep kaur lamba, farrukh faraz, shruti tandon, kirti chawla case report abstract peripheral ossifying fibroma pof is a nonneoplastic growth on the. Cemento ossifying fibroma is a uncommon benign fibro osseous lesion commonly occurs in the young adults in the age group. Ossifying fibroma of is a slowgrowing, benign lesion of bone most commonly associated with the jaws. Synonyms of pof are peripheral cementifying fibroma, ossifying fibroepithelial polyp, peripheral odontogenic. Cementoossifying fibroma of the jaw journal unair universitas. The presence of chronic renal disease crd is a predisposing factor for the occurrence of soft and hard tissue lesions in the oral cavity. Commonly used synonyms include cementifying fibroma, peripheral. Other terms used to describe this lesion include peripheral cementifying fibroma. Rhammerk interaction induces proliferative activities of cementifying fibroma cells through a.
In 1971, the world health organization who classified cementum containing lesions into four types that include fibrous dysplasia, ossifying fibroma, cementifying fibroma, and cementoossifying fibroma. Central cementoossifying fibroma behaves like, a benign bone neoplasm. Diagnostic pathology two cases of multiple ossifying fibromas in the jaws tingting wang 1 ran zhang 0 lin wang 1 yan chen 0 qing dong 1 tiejun li 0 2 3 0 department of oral pathology, peking university school and hospital of stomatology, 22 south zhongguancun avenue, haidian district, beijing 81, pr china 1 department of oral medicine, hebei united university, school and hospital of. Fibrous dysplasia has margins which blend with the surrounding bone. The ossifying and cementifying fibromas are differentiated by their clinical, radiological, and histological findings. A definitive diagnosis is thus established upon also considering the clinical and radiological findings. The term cementifying fibroma was originally applied to the lesion of the mandibular incisor teeth now referred to as periapical cemental dysplasia pindborg. The following differences are recognized radiologically. This paper reports a case of multiple cementoossifying fibroma involving the maxilla and mandible of a 55yearold male. Cementifying fibroma is a rare benign fibroosseous tumor belonging to. Cementoossifying fibroma cof is a benign fibro osseous lesion of the jaws which has been described as a demarcated. Cemento ossifying fibroma is a benign, non odontogenic tumour of the jaw, a subdivision of.
The term ossifying fibroma has been used since 1927, and since 1968 cementumcontaining tumours have been grouped together. Ameloblastic fibrosarcoma mixed epithelial and mesenchymal tumors all benign odontoma ameloblastic fibroma ameloblastic fibroodontoma nonodontogenic tumors of the jaws benign. Cementoossifying fibroma a case report omics international. American journal of pharmacology and pharmacotherapeutics. The histological pattern of these lesions varies with the stages. The tumour had replaced one half of the body of the mandible. Many names have been used to describe this lesion osteofibroma, fibroosteoma, cementifying fibroma secondary to the tumors cell of origin. Unusually largesized peripheral ossifying fibroma john rr. However, the term cementifying ossifying fibroma was reduced to. Who in 1972 classified it in two types as ossifying fibroma and cementifying fibromas. A case of cementoossifying fibroma involving the right mandible is described in a 30 yearold female patient.
Peripheral ossifying fibroma, also known as ossifying fibrous epulis, is a gingival nodule which is composed of a cellular fibroblastic connective tissue stroma which is associated with the formation of randomly dispersed foci of mineralised products, which consists of bone, cementumlike tissue, or a dystrophic calcification. The lesion is considered part of an ossifying fibroma, but that. Cementoossifying fibroma cof are rare, benign neoplasms that usually arise from the mandible or maxilla. Pdf cementifying fibroma of the frontoethmoid complex. Case report bilateral cemento ossifying fibroma of mandible. The central matured ossified nodules were of low density on ct scans and high signal intensity on t1 and t2weighted. Central cementoossifying fibroma is a fibroosseous lesion causing slow expansion of the involved bone and is usually manifested after attaining significant growth. Pdf cementifying fibroma clinical characteristics, histological. A 37yearold female patient undergoing chronic haemodialysis reported to our.
Cementoossifying fibroma is a benign neoplasm characterized by replacement of. We report a case of cementoossifying fibroma that presented as a large extraosseous mass in the masticator and parapharyngeal space. Almost all cases of ossifying and cementifying fibromas reported previously occur as a solitary lesion. Ct scanning and mr imaging showed a large extraosseous mass with central conglomerated, wellmatured ossified nodules and fatty marrow. Slow and progressive, cementoossifying fibroma is a rare benign tumor that reaches the maxilla and more frequently the mandible.
Many types of localized reactive lesions are seen on the gingiva, including focal fibrous hyperplasia, pyogenic granuloma, peripheral giant cell granuloma, and peripheral ossifying fibroma pof. Cementoossifying fibroma presenting as a mass of the. Peripheral ossifying fibroma europe pmc article europe. Shipra arora et al treatment of peripheral ossifying. Cementoossifying fibroma cof is considered by most as relatively rare, benign, nonodontogenic neoplasm of the jaw bones and other.
High power histopathological picture showing lamellar bone with osteoblastic rimming and psammomatouslike nodules and calcifications in the fibrous stroma haematoxylineosin x larger lesions with size over 80 mm in their greatest diameter have been termed as giant ossifying fibroma. Cementifying fibroma is considered as a benign, osseous tumour, which arises from the periodontal ligament and is composed of varying amounts of cementum, bone and fibrous tissue. The cementoossifying fibroma cof is a mesodermal, nonodontogenic tumour of ectopic multipotential periodontal membrane blast cells. Cementoossifying fibroma cof is considered by most as relatively rare, benign, nonodontogenic neoplasm of the. Treatment of peripheral ossifying fibroma using er,cr. Rhammerk interaction induces proliferative activities of. Traditionally, this type of lesion was subclassified histologically into ossifying fibroma and cementifying fibroma according to the hard tissues formed, but both types are now known by the unified term, ossifying fibroma. Cementoossifying fibroma in a patient with endstage. The cementoossifying fibroma cof is an uncommon benign fibroosseous lesion composed of fibrocellular component and calcified materials like cementum and woven bone. Peripheral ossifying fibroma pof is one of the several common reactive hyperplastic inflammatory lesions of the gingiva. Here we present a case of 18year old female having slow growing painless swelling on left side of mandible over 2year period. Pdf cemento ossifying fibroma of the maxillaa case report. Synonyms of pof are peripheral cementifying fibroma, calcifying or ossifying fibroid epulis, and peripheral fibroma with calcification. Ossifying fibroma of is classified as, and behaves like, a benign bone.
Cementifying fibroma definition of cementifying fibroma by medical dictionary s. A case of cementifying fibroma with odontoma of the mandible, combining sturgeweber syndrome and goldenhar syndrome. It is very closely related to other fibroosseous lesions like fibrous dysplasia, cemental periapical dysplasia and other calcifying odontogenic cysts and tumour. Peripheral cementoossifying fibroma is a relatively rare tumour classified between fibroosseous lesions. This lesions commonly seen in women in 3rd and 4th decade of life. It is often encapsulated and predominantly located in the mandible, and presents as a slowgrowing lesion, but may cause deformity if left untreated. Aarthinisha sree balaji dental college and hospital, bharath university, chennai, india abstract.
A case of cementifying fibroma with odontoma of the. Ii issue 1 janmar 2010 4 fibroma may be seen with a similar mottled appearance to that seen in fibrous dysplasia. The pathological examination confirmed the ossifying fibroma. Cementifying fibroma is considered as a benign, osseous tumour, which. It is aggressive, locally destructive, and has a high. The term ossifying fibroma has been used since 1927, and since 1968, cementum containing tumors has been grouped together. Usually in the jaw region the lesions are found mostly in the tooth bearing area. Pdf giant cementifying fibroma rohit sharma academia. The concept of fibroosseous lesions of bone has evolved over the last several decades and now includes two major entities. Pdf introduction cementifying fibroma cf is a fibroosseous lesion which produces cementum. Fibrous dysplasia indistinct borders which blend imperceptible with. It usually arises from the inter dental papillae1 and represents upto 2% of all lesions that are biopsied.
Fibroosseous tumors ossifying fibroma juvenile ossifying fibroma langerhans cell disease. Mandibular cementifying fibroma and cementoblastoma 5478 int j clin exp med 2017. There have been occurrences in other bones, most commonly the tibia. Ossifying fibroma of is a benign, nonodontogenic tumor of the jaw, a type of fibroosseous lesion. Several sections of the sample must be carefully examined, since. Surgical enucleation with curettage of the lesion of the patient mentioned in this case report. The definitive diagnosis of these lesions requires integration of its clinical, radiological and histological features. Cementoossifying fibroma is a benign growth, considered to originate from the periodontal ligament. Ossifying fibroma an overview sciencedirect topics. Only those reports of ofs that occurred in a series in the reporting authors caseload were considered. A 36 year old female with giant cementifying fibroma is presented. Appropriate management, to achieve local control and prevent destructive expansion, requires early diagnosis, which fine. Cementoossifying fibroma is a relative rare lesion considered as an osteogenic tumor nonodontogenic with variable expressiveness.
Fibroosseous lesions refer to a collection of nonneoplastic intraosseous lesions that replace normal bone and consist of a cellular fibrous connective tissue within which nonfunctional osseous structures form. Eversole fibro osseous lesions are a diverse group of processes that are characterized by. Cementoossifying fibromas cofs are relatively rare, benign lesions. Ossifying fibroma always presents well defined margins. It is defined as a welldemarcated and occasionally encapsulated. The databases searched were the pubmed interface of medline and lilacs.
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